The Science Behind Korea’s Viral Salmon Sperm Injection

Korea’s salmon sperm injectable is gaining attention worldwide for its ability to boost collagen, improve elasticity, and strengthen the skin barrier, with minimal downtime, making it a surprisingly suitable alternative to traditional anti-wrinkle treatments.

Rejuran contains polynucleotides from salmon DNA (unusual, yes - but backed by science), and these molecules work deep within your skin to promote repair and regeneration. It may sound unexpected, but there’s solid research supporting how these ingredients work. And the skin-savvy team at My Body Vibes have seen firsthand how this Korean injectable is quietly becoming the go-to glow-up for clients who want results without the drama.

Our medical team have reported that patients notice their skin feels healthier and more resilient after treatment. So there seems to be real substance behind the hype of this viral salmon sperm treatment.

Today, we’ll be breaking down all the science behind this polynucleotide-based treatment so you can better understand how this salmon sperm treatment has ended up taking the world by storm, from Hollywood Boulevard to the Melbourne CBD.

What Are Polynucleotides and How Do They Work?

If you Google ‘salmon sperm treatment’, chances are a few different things will pop up, including the word ‘Rejuran’. Rejuran (brand name) is a cosmetic injectable skin rejuvenation treatment that uses polynucleotides (derived from salmon DNA) to stimulate natural skin repair and regeneration. If you were looking to book a salmon sperm treatment for yourself, it will most likely be referred to as a Rejuran Treatment. 

At the heart of the Rejuran Treatment (also called Rejuran Healer) are polynucleotides, which come from salmon DNA. Polynucleotides are long chains of molecules that make up DNA, and they play a key role in cellular repair and regeneration. 

Once injected, polynucleotides are understood to play a role in reducing inflammation, encouraging tissue repair, and activating fibroblasts - the cells involved in collagen and elastin production. 

Today, polynucleotide injectables are used to address a large variety of skin concerns, including acne scarring, discolouration, fine lines and wrinkles. These injectables are designed to target the skin at a deeper level than many surface treatments, supporting the skin’s natural repair processes. As a result, some patients may observe improvements in texture, tone, and overall skin condition over time.

Salmon Sperm Injection?! Here’s The Science

If you’re calling it ‘the salmon sperm injection,’ you probably don’t know how it works. Let’s set the record straight on what polynucleotides really do and why your derm loves them. Yes, Rejuran uses polynucleotides extracted from salmon DNA. And no, it’s not just some quirky K-beauty gimmick. There’s real science (and some pretty smart reasoning) behind why salmon DNA is the star ingredient in this beauty treatment.

First, salmon DNA is incredibly biocompatible with human skin. That means your body recognises it, doesn’t react negatively to it, and can actually use it to support cellular functions. Compared to other sources, salmon DNA has a very similar structure to human DNA, which makes it especially effective at integrating into the body’s repair processes.

Second, salmon DNA is rich in polynucleotides. Studies have shown that these polynucleotides can help speed up wound healing, improve microcirculation, and enhance elasticity. That’s why polynucleotide injectables are often used not only for anti-aging, but also to treat acne scars, sun damage, and weakened skin barriers.

My Body Vibes Salmon DNA Treatment: Benefits and Results

The Key Benefits of Polynucleotides

People are turning to Rejuran for good reason. It doesn’t just sit on the surface - it restores your moisture levels from the inside out. Plus, it strengthens the outer barrier and minimises pores, which means your skin becomes more resilient and better able to handle environmental stressors like pollution and harsh weather. 

There’s minimal downtime. You might notice some mild redness or swelling right after treatment, but it usually fades quickly - so you can get back to your day feeling confident and looking refreshed.

Always consult with a qualified practitioner to determine whether this treatment is right for your individual skin concerns and needs.

Where Can Polynucleotide Injections Be Used?

One of the things that sets Rejuran apart from other treatments is how it's used. Instead of focusing on just one area (like the cheeks, temples, or forehead), it’s designed to treat the entire face. 

Rejuran is also commonly used on the neck, where the skin is thinner and often shows signs of aging sooner. By treating these areas together, polynucleotide injectables aim to create a smoother, more unified appearance from face to neck.

Rejuran Eye Before & After

There’s also a special version called Rejuran I (that’s “eye” for short), which is formulated specifically for the delicate under-eye area. So if tired-looking eyes or crepey dark circles are a concern, Rejuran I aims to offer a targeted solution that works in harmony with your body’s repair processes, leaving your eyes looking brighter, smoother, and more awake.

Why Are Polynucleotides So Popular?

Part of what makes Rejuran so loved is how well it plays with other treatments. It can be combined with wrinkle-relaxing injections to tackle both texture and expression lines at once. You might also see it paired with medik 8 peels, Tixel, or IPL to support healing, hydration, and collagen production after those more intensive treatments. It’s often used in a treatment plan that evolves over time, designed by a practitioner to suit your unique needs.

Most people start with a series of three sessions, spaced a few weeks apart, to build up that deep-skin rejuvenation. Polynucleotide injections are not a substitute for wrinkle-reducing treatments - they’re a complement. While wrinkle injections temporarily reduce muscle movement, the nutrients from salmon DNA support the skin’s structure by stimulating collagen.

As research and practitioner experience grows, it's becoming a popular addition to long-term skin care routines.

Why Salmon DNA Reigns Supreme

Rejuran vs. Botox: Common antiwrinkle treatments are typically neuromodulators made from botulinum toxin type A, and they work by temporarily paralysing muscles to reduce the appearance of dynamic wrinkles, like frown lines, crow’s feet, and forehead creases.

This treatment aims to deliver fast, visible results within days, making it a go-to for smoothing expression lines. However, botulinum toxin type A doesn't improve skin texture or quality, and the effects typically wear off after 3-4 months.

Rejuran aims to go deeper, healing and strengthening the skin from within. For long-term skin health, natural collagen stimulation, and visible skin rejuvenation, polynucleotide injectables offer more regenerative benefits.

Kim Kardashian & Jennifer Aniston Have Had Salmon Sperm Injections

Let’s be real: if the Kardashians are doing it, the rest of the world is at least curious. Kim casually mentioning a salmon DNA facial on The Kardashians might sound like peak celebrity absurdity, but it also signals that this isn’t just a fringe treatment anymore. When the family that basically sets the internet's beauty agenda gives something the nod, people listen. And when Jennifer Aniston’s also in the chair asking the same “Wait, how?” questions that we are, you know, it’s officially gone mainstream.

Say what you will about reality TV royalty, but they’ve always been ahead of the curve when it comes to beauty innovation. From vampire facials to LED masks and now polynucleotides from salmon DNA, they’re often the first to try the “weird” stuff - so the rest of us don’t have to. And maybe, just maybe, they’re onto something (again).

Want to know more about salmon sperm treatments? Book a consultation with our medical team at My Body Vibes to speak directly with our cosmetic specialists. We can help you determine whether this treatment is suitable for you.